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Fig. 12 | Journal of Translational Medicine

Fig. 12

From: Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease

Fig. 12

Discovery and validation of a new PT subgroup with response to losartan treatment. A: GO enrichment analysis of the marker genes in PT14 and PT10. B: Gene-scoring analysis of key events of mitochondrial homeostasis in PT4-PT6 subclusters. C: As losartan treatment progresses, PT4 cells transform into PT5 and PT6 cell subtypes. D-E: Changes in Specific Expressed Genes during transformation process. F: Heatmap of top differentially expressed transcripts of pseudo time functions among three subtypes. G: Representative immunofluorescence images from each group

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Journal of Translational Medicine

ISSN: 1479-5876

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