Circ-ITCH promotes the ubiquitination degradation of HOXC10 to facilitate osteogenic differentiation in disuse osteoporosis through stabilizing BRCA1 mRNA via IGF2BP2-mediated m6A modification

Zhong, Da; Li, Xi; Yin, Zhen; Chen, Peng; Li, Yusheng; Tian, Jian; Wang, Long; Liu, Hua; Yin, Ke; Zhu, Lemei; Kong, Lingyu; Chen, Kunli; Li, Yaochun; Hong, Chungu; Wang, Chenggong

doi:10.1186/s12967-024-06050-5

Journal of Translational Medicine

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Last updated: Tue, 20 May 2025 6:01:54 Z

Circ-ITCH promotes the ubiquitination degradation of HOXC10 to facilitate osteogenic differentiation in disuse osteoporosis through stabilizing BRCA1 mRNA via IGF2BP2-mediated m⁶A modification

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ISSN: 1479-5876

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