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Fig. 9 | Journal of Translational Medicine

Fig. 9

From: Development of autonomic innervation at the venous pole of the heart: bridging the gap from mice to human

Fig. 9

Autonomic nerve markers at the pulmonary vein in mice and humans at late cardiogenesis. A–D Mouse sections of the pulmonary vein at E18.5. The coronary sinus and dorsal right atrial wall with the orifice of the right superior caval vein and venous valves is also discernible. A’–D’ Human sections of the pulmonary vein at 13 WGA. A–D. In mouse embryos at this stage, most nerves at the venous pole co-express both ChAT and TH. A’–D’ Also in the human embryo of 13 WGA, many nerve cells co-express both ChAT and TH. Scalebars: 200 μm. Br: pulmonary bronchi; CS: coronary sinus; LA/RA: left/right atrium; LV/RV: left/right ventricle; Oe: oesophagus; PV: pulmonary vein

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