Fig. 8

hEnSC-derived small EVs activates the PI3k/Akt signaling pathway in PC12 cells. a Western blot data demonstrated increased expression of PI3k/Akt in treated PC12 cells by increasing small EVs concentration; b Bar graph of western blot densitometry. Analysis was done by image J. ns. not significant/***P < 0.001/****P < 0.0001. Each experiment was investigated in triplicate (n = 3)