Fig. 7
From: Reversal gene expression assessment for drug repurposing, a case study of glioblastoma
Concentration–response curves of Clofarabine and Ciclopirox in iPSC-derived astrocytes and GBM cells. A: Concentration–response curves of Clofarabine in astrocytes; B: Concentration–response curves of Clofarabine in GBM cells; C: Clofarabine’s IC50 on astrocytes (green bar) and GBM cells (red orange bars); D: Concentration–response curves of Ciclopirox in astrocytes; E: Concentration–response curves of Ciclopirox in GBM cells; F: Ciclopirox's IC50 on astrocytes (green bar) and GBM cells (red orange bars); In A, B, D, and E, Each data point is presented as mean ± SD; n = 4–6 biological replicates for each condition