Fig. 1

Development and risk classification of NK-PSS-M. (A) Univariate Cox regression forest plot, with colors indicating the significance of the variables. (B) Multivariate Cox regression forest plot, with diamonds representing hazard ratios (HRs) and line segments representing confidence intervals. (C) The optimal risk score cut-off value is calculated using maximally selected rank statistics to classify patients into high- and low-risk groups. (D) Density plot of the NK MDS risk scores from 237 patients in the training set. The x-axis represents the risk score calculated by NK-PSS-M; the vertical dashed line represents the cut-off value. The groups are represented by their abbreviated names, and the numbers below indicate the proportion of each group. VL, very low; L, low; M, intermediate; H, high; VH, very high