Table 2 Clinicopathological characteristics of biliary tract cancer (BC) and pancreatic cancer (PC) patients, and their age- and sex-matched healthy controls

Age (years)

Median (range)

69 (53–82)

69.5 (51–82)

69 (51–82)

0.963

70 (51–83)

68 (51–82)

69.5 (51–83)

0.772

Sex

N (%)

M

5 (35.7)

5 (35.7)

10 (35.7)

1.000

11 (52.4)

11 (52.4)

22 (52.4)

1.000

F

9 (64.3)

9 (64.3)

18 (64.3)

10 (47.6)

10 (47.6)

20 (47.6)

Weight (kg)

Median (range)

59.8 (45.5–80.5)

65.6 (52.5–86.0)*

60.7 (45.5–86.0)

0.244

55.4 (40.8–87.3)

66.0 (42.2–77.2)^*

57.6 (40.9–87.3)

0.076

BMI (kg/m²)

Median (range)

22.4 (17.9–29.0)

24.9 (18.8–29.1)*

23.0 (17.9–29.1)

0.125

21.9 (17.8–27.1)

24.9 (19.7–28.7)^*

22.5 (17.8–28.7)

0.006

Alcohol consumption

N (%)

Yes

4 (30.8)

7 (50.0)

11 (40.7)

0.533

6 (33.3)

8 (44.4)

14 (38.6)

0.732

No

9 (69.2)

7 (50.0)

16 (59.3)

12 (66.7)

10 (55.6)

22 (61.1)

NA

0

0

0

0

0

0

Tobacco smoking

N (%)

Yes

2 (15.4)

2 (14.3)

4 (14.8)

1.000

1 (5.6)

1 (4.8)

2 (5.1)

1.000

No

11 (84.6)

12 (85.7)

23 (85.2)

17 (94.4)

20 (95.2)

37 (94.9)

NA

1

0

1

3

0

3

Severity of periodontitis^†

N (%)

Mild

0 (0.0)

0 (0.0)

0 (0.0)

1.000

0 (0.0)

0 (0.0)

0 (0.0)

1.000

Moderate

6 (46.2)

6 (54.5)

12 (50.0)

9 (45.0)

7 (50.0)

16 (47.1)

Severe

7 (53.8)

5 (45.5)

12 (50.0)

11 (55.5)

7 (50.0)

18 (52.9)

NA

1

3

4

1

7

8

Histologic subtype

N (%)

Adenoca

14 (100.0)

19 (90.5)

Sqcc

0 (0.0)

0 (0.0)

NA^‡

0

2 (9.5)

Tumor differenciation

N (%)

WD

3 (30.0)

0 (0.0)

MD

5 (50.0)

8 (80.0)

PD

2 (20.0)

2 (20.0)

NA

4

11

Lymph node metastasis

N (%)

Negative

6 (42.9)

8 (38.1)

Positive

8 (57.1)

13 (61.9)

NA

0

0

Distant metastasis

N (%)

M0

14 (100.0)

17 (81.0)

M1

0 (0.0)

4 (19.0)

NA

0

0