Table 1 Clinicopathological characteristics of esophageal cancer (EC) and gastric cancer (GC) patients, and their age- and sex-matched healthy controls

Age (years)

Median (range)

68 (49–86)

68 (48–82)

67 (48–86)

0.232

67 (48–80)

68 (49–80)

67.5 (48–80)

0.965

Sex

N (%)

M

36 (85.7)

24 (77.4)

60 (82.2)

0.544

10 (52.6)

10 (52.6)

20 (52.6)

1.000

F

6 (14.3)

7 (22.6)

13 (17.8)

9 (47.4)

9 (47.4)

18 (47.4)

Weight (kg)

Median (range)

63.2 (39.8–81.7)

75.2 (52.45–91.1)^*

68.0 (39.8–91.1)

0.006

54.0 (36.9–71.8)

68.2 (55.2–86.0)^*

57.5 (36.9–86.0)

0.008

BMI (kg/m2)

Median (range)

23.3 (14.6–27.8)

25.5 (18.8–29.3)^*

24.1 (14.6–29.3)

0.009

20.9 (13.9–26.6)

24.9 (21.0–29.1)^*

22.1 (13.9–29.1)

0.003

Alcohol consumption

N (%)

Yes

21 (63.6)

15 (53.6)

36 (59.0)

0.593

10 (55.6)

6 (46.2)

16 (51.6)

0.879

No

12 (36.4)

13 (46.4)

25 (41.0)

8 (44.4)

7 (53.8)

15 (48.4)

NA

9

3

12

0

0

0

Tobacco smoking

N (%)

Yes

7 (21.2)

3 (10.0)

10 (15.9)

0.308

3 (16.7)

0 (0.0)

3 (8.3)

0.229

No

26 (78.8)

27 (90.0)

53 (84.1)

15 (83.3)

18 (100.0)

33 (91.7)

NA

9

1

10

1

1

2

Severity of periodontitis^†

N (%)

Mild

0 (0.0)

1 (3.7)

1 (1.5)

0.008

0 (NA)

2 (11.8)

2 (11.8)

NA

Moderate

4 (10.3)

10 (37.0)

14 (21.2)

0 (NA)

9 (52.9)

9 (52.9)

Severe

35 (89.7)

16 (59.3)

51 (77.3)

0 (NA)

6 (35.3)

6 (35.3)

NA

3

4

7

19^‡

2

21

Histologic subtype

N (%)

Adenoca

0 (0.0)

19 (100.0)

Sqcc

41 (100.0)

0 (0.0)

NA^§

1

0

Tumor differenciation

N (%)

WD

4 (13.3)

1 (5.6)

MD

3 (10.0)

4 (22.2)

PD

23 (76.7)

13 (72.2)

NA

12

1

Lymph node metastasis

N (%)

Negative

27 (65.9)

11 (61.1)

Positive

14 (34.1)

7 (38.9)

NA

1

1

Distant metastasis

N (%)

M0

41 (97.6)

16 (88.9)

M1

1 (2.4)

2 (11.1)

NA

0

1