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Table 2 Characteristics of the patients with U. urealyticum, U. parvum, and M. hominis positivity

From: Epidemiological and clinical characteristics of ammonia-producing microorganisms in the lungs of patients with severe pneumonia: a multicentre cohort study

 

Ureaplasma urealyticum (n = 17)

Ureaplasma parvum (n = 19)

Mycoplasma hominis (n = 13)

 ≥ two pathogens (n = 6)

Clinical symptoms, n (%)

 Drowsiness

2 (11.8)

2 (10.5)

1 (7.7)

2 (33.3)

 Coma

5 (29.4)

10 (52.6)

4 (30.8)

2 (33.3)

 Epilepsy

0 (0)

2 (10.5)

0 (0)

0 (0)

History of transplantation, n (%)

 Kidney

4 (23.5)

0(0)

0(0)

1 (16.7)

 Lung

0 (0)

3 (15.8)

1 (7.7)

0 (0)

Antimicrobial treatment before clinical metagenomics testing, n (%)

 Macrolides

1 (5.9)

0 (0)

0 (0)

0 (0)

 Quinolones

2 (11.8)

4 (21.1)

1 (7.7)

1 (16.7)

 Blood ammonia test, n (%)

4 (23.5)

4 (21.1)

4 (30.8)

1 (16.7)

 Blood ammonia, median (IQR)

69.5 (38.2, 132.2)

22.5 (10.2, 34.2)

36.8 (30.9, 39.0)

432.0

 Head CT scan, n (%)

11 (64.7)

14 (73.7)

9 (69.2)

5 (83.3)

 Cerebral edema

2 (18.2)

9 (64.3)

3 (33.3)

1 (20.0)

 Lumbar puncture, n (%)

1 (5.9)

3 (15.8)

2 (15.4)

3 (50.0)

 Intracranial pressure, cm H2O, median (IQR)

270.0

170.0 (127.5,310.0)

250.0 (250.0,250.0)

200.0 (150.0,240.0)

Therapeutic drug, n (%)

 Macrolides

1 (5.9)

0(0)

0(0)

2 (33.3)

 Quinolones

2 (11.8)

4 (21.1)

3 (23.1)

3 (50.0)

 Tetracyclines

2 (11.8)

1 (5.3)

1 (7.7)

0(0)

 Improvement in patients with treatment, n (%)

2 (40.0)

3 (60.0)

2 (50.0)

4 (80.0)

  1. SD standard deviation, CT computed tomography