Fig. 2

(a) The dissimilarity ranks between and within classes based on ANOSIM analysis of overall metabolites. (b) The score plot of principal component analysis based on 198 metabolites differential between groups. (c) The relative abundances of 8 most abundant differential metabolites in children with ASD and neurotypical controls. (d) KEGG pathways enriched by metabolites with lower abundances in children with ASD. (e) KEGG pathways enriched by metabolites with higher abundances in children with ASD. (f) Relative abundances of metabolites enriched in KEGG pathway ‘Steroid hormone biosynthesis’ in all participants