Fig. 3

Changes in methylation regulatory patterns during differentiation. a–c mRNA expression of methylation regulatory enzymes (a) DNMT1, (b) DNMT3A, and (c) TET3 during differentiation (n = 6 samples). d–g Expression of corresponding (d) methylation regulatory proteins and their (e–g) quantification (e) TET3, (f) DNMT1, (g) DNMT3A, (n = 6 samples). Data were shown as mean ± standard deviation. Statistical analysis was performed using one-way ANOVA with Tukey’s HSD post-hoc test. ***p < 0.001 vs Control group. ^##p < 0.01, ^###p < 0.001 vs Control 7dpi group