Fig. 7
From: Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1

Lung-specific transgenic expression of Fcnb protected mice against lung fibrosis. (A) Work flow of murine models. (B) The body weight change during BLM treatment was monitored (n = 6–15 per group). (C) The lungs from WT and OE-Fcnb mice were stained with Masson’s trichrome (n = 6 per group). (D) Histological analysis of the severity of lung fibrosis in mice after BLM induction (n = 6–15 per group). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 by one-way ANOVA (C) or two-way ANOVA (A). Fcnb, ficolin-B