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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Esophageal microbial dysbiosis impairs mucosal barrier integrity via toll-like receptor 2 pathway in patients with gastroesophageal reflux symptoms

Fig. 4

Transcriptome analysis between GERD/FED and healthy volunteers. A. DEGs in GERD patients compared with HV. B. DEGs in FED patients compared with HV. C. Fold change of TLR2 expression in GERD patients compared to healthy volunteers. GERD vs. HV = 26.8 ± 3.4 vs 2.2 ± 0.4, P < 0.001. D. Fold change of TLR2 expression in FED patients compared to healthy volunteers. FED vs. HV = 30.2 ± 3.9 vs 2.2 ± 0.4, P < 0.001. Abbreviation: GERD: gastroesophageal reflux disease; FED: functional esophageal disorders; HV: healthy volunteers; TLR: toll-like receptor; DEGs: differentially expressed genes; ***: P < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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