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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study

Fig. 7

Comparison of the efficacy of autologous adipose-derived mesenchymal stem cells (ADSCs) and miR-195-5p. A Microscopy assessment of autologous ADSCs morphology from passage 0 (P0) to P3, showing their adhesiveness and fibroblastoid shape. B Osteogenic, adipogenic, and chondrogenic differentiation of ADSCs. C Flow cytometry detection of ADSC surface markers CD29, CD90, CD45, and CD11b/c. D In vivo imaging of ADSC homing in intrauterine adhesions. EG H&E staining of uterine morphology with statistical analysis of endometrial thickness and gland number. H, I Assessment of fibrotic area in the endometrium using Image Pro Plus 6.0 and Masson staining. JM Western blot analysis of ECM and myofibroblast transdifferentiation markers (α-SMA, collagen I, and vimentin) in IUA

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