Fig. 5

MiR-195-5p overexpression inhibits migration, ECM deposition, and myofibroblast transdifferentiation of ESCs treated with TGF-β. A Verification of miR-195-5p expression in the cell model by RT-PCR. B–H Expression of ECM-related and myofibroblast transdifferentiation markers (α-SMA, collagen I, and vimentin) analyzed by Western blot and RT-PCR. I, J Healing ability after miR-195-5p mimic treatment. K, L Migration ability after miR-195-5p mimic treatment. (ns = not significant, *P < 0.05, **P < 0.01, ****P < 0.001)