Fig. 5

miR-4712-5p inhibits colon cancer cell progression via hBD-1 (A): The qRT-PCR detected the miR-4712-5p expression at the RNA level. (B): CCK-8 cell proliferation curve; (C): The cell migration ability was using the scratch assay. (D): MDC staining for intracellular autophagic vesicles; (E): Western blotting for detecting the AKT/mTOR signaling pathway related proteins, LC3II/I ratio, and Beclin-1 expression, the representative Western blotting bands, and the quantification of protein expression. Versus. inhibitor-NC, *p< 0.05, **p< 0.01. Versus. inhibitor-NC+hBD-1, #p < 0.05, ##p< 0.01. Versus. miR-4712-5p inhibitor, $p<0.05, $$p<0.01