Fig. 5
From: Right ventricular volume overload reboots cardiomyocyte proliferation via immune responses
CsA inhibits prepubertal CM proliferation rebooting in RVVO (A) CsA reduced the number of DEGs. (B) CsA shifted the RVVO-changed gene expression profile toward the normal (sham) profile, as indicated by the PCA of the DEGs. (C) CsA shifted the RVVO-changed gene expression profile toward the normal (sham) profile, as indicated by the cluster analysis of the DEGs. (D) Representative immunofluorescence staining of pH3-positive CMs. (E) Quantification of pH3-positive CMs. Note: CsA = CsA + VO, CsA withou VO were comparable to the sham group