Fig. 1
From: Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction
Expression of MAPL in heart tissue and H9C2 cardiomyocytes were upregulated after LPS stimulation or CLP Challenge. A. H9C2 cardiomyocytes were treated with LPS (20 µg/ml) for 1, 3, 6, 12, and 24 h, and the expression of MAPL in mitochondria of cardiomyocytes was analyzed by western blot (*P < 0.05, **P < 0.01, ***P < 0.001, n = 6 repeated experiments). B. H9C2 cardiomyocytes were treated with LPS for 24 h, then immunofluorescence staining was performed to detect the expression of MAPL (scale bar = 10 μm. n = 5 repeated experiments). C. Heart tissues were harvested 3, 6, and 12 h after CLP, and the expression of MAPL in mitochondria of heart tissues was analyzed by western blot (*P < 0.05, n = 5 for each group)