Fig. 5

(A) VTN levels of healthy controls and “long-term” KTx patients stratified by percentage of fibrosis, with descriptive statistics at the bottom. (B) VTN levels normalized by urinary creatinine of healthy controls and “long-term” KTx patients stratified by percentage of fibrosis, with their descriptive statistics at the bottom. Statistical differences are indicated for *p < 0.05, ***p < 0.001 and ****p < 0.0001 by a Kruskal Wallis test with Dunn’s post-hoc analysis. (C) VTN levels obtained by ELISA stratified regarding the percentage of fibrosis observed in the kidney biopsies. Statistical differences are indicated for ****p < 0.0001 by a Mann-Whitney test. (D) ROC curve based VTN as a unique biomarker to differentiate the two groups of patients (healthy controls vs. fibrotic patients). Cntrl, Healthy controls; VTN, Vitronectin; U.Creat, urinary creatinine