Fig. 4

Analysis of the “long-term” KTx patients. Venn diagrams showing the number and percentage of patients with fibrosis that would be detected by VTN or VTN/U.Creat levels, albuminuria levels or both, without a biopsy. (A and B) VTN, VTN/U.Creat, and albuminuria threshold levels have been stablished based on the ROC curves of these parameters (VTN considered positive > 12.80 ng/mL; VTN/U.Creat considered positive > 0.13; albuminuria considered positive > 95.65 mg/g). (C and D) The clinical albuminuria threshold (> 300 mg/g) was considered for the analysis. VTN, vitronectin; U.Creat, urinary creatinine