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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: From inflammation to depression: key biomarkers for IBD-related major depressive disorder

Fig. 2

Integration and differential expression analysis of the IBD dataset. A. Volcano plot of DEGs in IBD intestinal tissue samples and heatmap of the top 50 upregulated and downregulated DEGs. B. Volcano plot of DEGs in IBD peripheral blood samples and heatmap of the top 50 upregulated and downregulated DEGs. Upregulated genes are represented by red dots, while downregulated genes are represented by blue dots. C. Venn diagrams showing the intersection of intestinal tissue and peripheral blood samples with secreted protein genes, resulting in 463 IBD-related secreted protein genes and 37 IBD-PBMC-related secreted protein genes. Further intersection yielded 484 IBD-related secreted protein genes

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