Fig. 7
Subgroup analysis for wound closure rate in diabetic and non-diabetic wound healing model. Subgroup analysis is conducted for mice wound healing studies administering MSC-EVs with similar modification, treatment dose and administration route. Each row represents pooled estimate data from studies within that subgroup. Data is presented as a forest plot with standardized mean difference and 95% confidence intervals. I2 value represents the statistical heterogeneity within each subgroup. Effect sizes > 0 favours MSC-EVs treatment and < 0 favours control. The ‘Overall Efficacy’ is a pooled estimate effect of MSC-EVs on wound closure rate from all studies combined