Fig. 6
Subgroup analysis for wound closure rate in non-diabetic wound healing model. Each row represents pooled estimate data from studies within that subgroup. Data is presented as a forest plot with SMD and 95% confidence intervals. I2 value represents the statistical heterogeneity within each subgroup. Effect sizes > 0 favours MSC-EVs treatment and < 0 favours control. The ‘Overall Efficacy’ is a pooled estimate effect of MSC-EVs on wound closure rate from all studies combined. ADSCs: adipose mesenchymal stem cells; BMMSCs: bone marrow mesenchymal stem cells; ucMSCs: umbilical cord mesenchymal stem cells; JMMSCs: jaw bone marrow mesenchymal stem cells; OOM-SCs: facial tissue-derived orbicularis oculi muscle stem cells; FDMSCs: fetus skin-derived mesenchymal stem cells; AECs: amniotic epithelial cells