Table 1 Summary of demographic and clinical features of patients with acromegaly
Clinical Feature | |
|---|---|
Number of patients | n = 40 |
Sex | |
Females | 25/40 (62.5%) |
Males | 15/40 (37.5%) |
Age at surgery (years; median (range)) | 40 (22–74) |
GH (µg/dL; median (range)) | 10.1 (0.89–171) |
IGF-1 (µg/dL; median (range)) | 704.5 (166–1600) |
Tumor size - max. diameter (mm; median (range)) | 18 (5.1–77) |
Invasive tumor growth | |
Invasive tumors (Knosp grade III, IV) | 15/40 (37.5%) |
Noninvasive tumors (Knosp grade 0, I, II) | 25/40 (62.5%) |
Granulation pattern | |
DG somatotroph tumors | 23/40 (57.5%) |
SG somatotroph tumors | 17/40 (42.5%) |
GNASmutation | 8/40 (20%) |