Explore genetic susceptibility association between viral infections and Guillain-Barré syndrome risk using two-sample Mendelian randomization

Table 1 Sensitivity analyses results

Exposures	MR-PRESSO global test p_value	Heterogeneity				Horizontal pleiotropy		Leave_one_out test All SNPs p_value
		MR egger		Inverse variance weighted		MR egger
		Cochran’Q	p_value	Cochran’Q	p_value	Egger intercept	p_value
HIV	0.310	9.969	0.190	10.174	0.253	− 0.045	0.715	0.023
COVID-19 (SARS-CoV-2)	0.797	21.724	0.751	28.000	0.792	0.012	0.834	0.275
Varicella (VZV)	0.487	2.708	0.608	4.122	0.532	0.227	0.300	0.543
Herpes zoster (VZV)	0.240	9.860	0.275	11.152	0.265	− 0.092	0.336	0.603
HSV	0.515	6.437	0.376	6.512	0.481	0.040	0.800	0.280
EBV	0.380	21.481	0.369	22.090	0.394	− 0.053	0.460	0.229
HBV	0.781	10.243	0.674	10.769	0.704	− 0.040	0.481	0.179
Influenza	0.889	2.634	0.955	4.471	0.878	0.151	0.212	0.917

ISSN: 1479-5876