The correlation of GluR3B antibody with T lymphocyte subsets and inflammatory factors and their role in the progression of epilepsy

Table 5 Comparison of peripheral blood cytokine levels in drug-resistant epilepsy, drug-responsive epilepsy, drug-naïve epilepsy, and healthy controls

	units	Drug-resistant patients (n = 64)	Drug-responsive patients (n = 41)	Drug-naïve patients (n = 66)	Healthy control (n = 40)	P
IL-1β [M (P₂₅,P₇₅)]	pg/ml	6.4 (2.5,9.7)	4.7 (1.6,8.2)	4.3 (1.3,8.3)	2.8 (2.1,6.6)	0.069
IL-2 [M (P₂₅,P₇₅)]	pg/ml	2.1 (1.0, 36.4)	1.7 (1.0, 3.2)	1.6 (0.8, 11.2)	1.7 (1.3, 2.5)	0.28
IL-4 [M (P₂₅,P₇₅)]	pg/ml	1.4 (0.8,10.0)	1.2 (0.9,2.7)	1.3 (0.8,4.0)	1.0 (0.9,2.6)	0.44
IL-5 [M (P₂₅,P₇₅)]	pg/ml	2.6 (1.5, 4.3)	2.5 (1.2, 5.8)	1.9 (1.1, 4.3)	2.4 (1.2, 3.1)	0.12
IL-6 [M (P₂₅,P₇₅)]	pg/ml	2.6 (1.6, 4.6)	3.0 (2.1, 6.1)	2.4 (1.4, 4.9)	2.3 (1.6, 3.8)	0.31
IL-8 [M (P₂₅,P₇₅)]	pg/ml	7.4 (2.5, 12.6)	1.4 (0.4, 4.8)	3.1 (0.8, 8.1)	1.0 (0.6, 2.4)	< 0.0001
IL-10 [M (P₂₅,P₇₅)]	pg/ml	1.4 (0.8, 1.8)	1.3 (0.8, 1.7)	1.3 (0.8, 1.7)	0.9 (0.8, 1.5)	0.11
IL-12p70 [M (P₂₅,P₇₅)]	pg/ml	1.8 (1.0, 3.5)	1.6 (1.0, 2.6)	1.7 (0.8, 2.5)	1.4 (0.9, 2.0)	0.20
IL-17 [M (P₂₅,P₇₅)]	pg/ml	1.6 (1.1, 2.8)	1.6 (1.1, 3.1)	1.5 (0.9, 2.4)	1.3 (1.1, 1.9)	0.52
IFN-α [M (P₂₅,P₇₅)]	pg/ml	1.9 (1.0, 4.9)	1.6 (0.9, 4.5)	1.5 (0.8, 4.3)	1.2 (1.1, 1.5)	0.14
IFN-γ [M (P₂₅,P₇₅)]	pg/ml	7.1 (3.7, 10.8)	2.9 (1.6, 5.5)	3.1 (1.2, 5.6)	2.5 (1.3, 3.6)	< 0.0001
TNF-α [M (P₂₅,P₇₅)]	pg/ml	2.4 (1.5, 3.9)	2.3 (1.1, 3.9)	2.3 (1.2, 4.7)	2.1 (1.3, 2.5)	0.34

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