Fig. 6
From: Berberine-loaded PLGA nanoparticles alleviate ulcerative colitis by targeting IL-6/IL-6R axis
Results of the transcriptomics analysis and GSEA between groups (n = 5). A: Volcano plot of DEGs between UC and control groups; B: TPM expression of Il-6 between UC and control groups; C: TPM expression of Il-6Rα between UC and control groups; D: GSEA of inflammatory response pathway between UC and control groups; E: GSEA of interleukin 6 family signaling between UC and control groups; F: GSEA of Il-6 signaling pathway between UC and control groups; G: GSEA of Jak/Stat signaling pathway between UC and control groups; H: GSEA of Nf-κb Pathway between UC and control groups; I: Volcano plot of DEGs between BPL-NPs and UC groups; J: GSEA of inflammatory response pathway between BPL-NPs and UC groups; K: GSEA of interleukin 6 family signaling between BPL-NPs and UC groups; L: GSEA of Il-6/7 pathway between BPL-NPs and UC groups; M: GSEA of Jak/Stat signaling pathway between BPL-NPs and UC groups