Fig. 11

JQ1 inhibits the expression of Nlrp3/Lin9/Foxm1 in vascular neointimal hyperplasia. A Immunofluorescence analysis was conducted to evaluate the differential expression of Nlrp3 in the neointimal layer of the carotid arteries of SD rats following different treatment regimens (DAPI, blue; Nlrp3, green; α-SMA, red; scale bar: 50 μm; n = 8). B The variations in the fluorescence intensity of Lin9 expression were examined across different treatment groups (DAPI, blue; Lin9, green; α-SMA, red; scale bar: 50 μm; n = 7). C The variations in the fluorescence intensity of Foxm1 expression were examined across different treatment groups (DAPI, blue; Foxm1, green; α-SMA, red; scale bar: 50 μm; n = 7). D The expression differences of Nlrp3/Lin9/Foxm1 in the carotid artery tissues of SD rats were analyzed using western blot analysis (n = 3). Data are presented as mean ± SEM (ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001)