Fig. 1

Differential expression of NLRP3 in femoral artery tissue. Human vascular tissues were obtained from healthy donors and patients with a history of PTA or PCB. A HE staining and IHC assays were employed to assess the differences in NLRP3 expression between normal arteries and arteries derived from the PTA and PCB groups (scale bars: HE, 200 μm; IHC, 100 μm; n = 6 per group). B Differential expression of NLRP3 protein in arterial tissues was assessed using western blot analysis (N means sample ID; n = 6 per group). C The mRNA levels of NLRP3 were detected using qPCR (n = 6 per group). Data are presented as mean ± SEM (*p < 0.05, **p < 0.01, ***p < 0.001)