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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Integrative microbiome and metabolome profiles reveal the impacts of periodontitis via oral-gut axis in first-trimester pregnant women

Fig. 3

sPLS-DA analysis on microbial genera in the pregnant women with Perio (n = 31) and Non-Perio (n = 23). A sPLS-DA-selected important genera in subgingival plaques (SBP) in Component 1. Genera of “tie” (non-differentiated) of sPLS-DA were not shown. B sPLS-DA-selected important genera in feces (MST) in Component 1. Bar length represents loading coefficient weight of selected genera, ranked in ascending order of importance, bottom to top; bar color denotes the group in which the genus has the highest median abundance, red = Perio, blue = Non-Perio. The detailed sPLS-DA results are provided in Table S11. C Bar plots of AUROCs and Cliff’s deltas of sPLS-DA-selected genera in subgingival plaques, saliva and feces. ANOVA and pairwise Student’s t-test were performed. Enriched groups: Non-Perio, Perio and tie, equally contributed. Cliff’s deltas were calculated relative to Non-Perio. D Ratios (log2) of the abundance (counts) of Porphyromonas to Rothia in SBP and Coprococcus to Lachnoclostridium. Wilcoxon rank sum test. ROC of two ratio pairs for discriminating between Perio and Non-Perio

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