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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid metabolism

Fig. 8

Immune states in patients with non-aGVHD differ from those in healthy donors and patients with aGVHD. A UMAP plot of scRNA-seq data from PBMCs of healthy donors, patients with aGVHD and with non-aGVHD, with cell subtypes labeled. B Dot plots illustrating relative expression levels of selected genes in PBMCs obtained from healthy donors, patients with aGVHD, and patients with non-aGVHD. C mRNA expression levels of selected genes in bone marrow cells and splenic cells from control groups, mice with BM transplantation, and mice with aGVHD (day 4)

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