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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid metabolism

Fig. 7

Relationship between GPBAR1/NR1H2 expression and immune regulation in myeloid lineages through correlation analysis. A Volcano plots depicting the upregulated and downregulated DEGs in GPBAR1 and NR1H2-expressing macrophage-like cells in comparison to their respective controls. B Volcano plots illustrating the upregulated and downregulated DEGs in GPBAR1 and NR1H2-expressing CD14−CD16+ monocytes compared to their respective controls. C Representative immunofluorescence staining of CD45 and S100A9 in the small intestine of control or aGVHD mouse model groups. Scale bar, 50 µm. D Relevance of GPBAR1/NR1H2 in immune regulation

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Journal of Translational Medicine

ISSN: 1479-5876

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