Fig. 3
From: miR-876-3p is a tumor suppressor on 9p21 that is inactivated in melanoma and targets ERK
Effects of miR-876 overexpression on apoptosis, migration and invasion in melanoma cells. A, B Analysis of apoptotic rates with representative dot plots and bar graphs indicating percentage of total apoptotic C8161.9 (panel A) and A375 cells (panel B) stably expressing miR-876 compared to control-miR. C, D Migratory capacity of C8161.9 (panel C) and A375 cells (panel D) stably expressing miR-876 compared to control-miR. E, F Invasive capacity of C8161.9 (panel E) and A375 cells (panel F) stably expressing miR-876 compared to control-miR. Data are shown as the mean ± SEM. *P < 0.05 denotes statistically significant differences compared with control