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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Mutual exclusivity and co-occurrence patterns of immune checkpoints indicate NKG2A relates to anti-PD-1 resistance in gastric cancer

Fig. 6

LGMN+ macrophages recruit ICEP2 CD8+ T cells through CXCL16-CXCR6. A NicheNet predicts the ligand-receptor activities within cells and visually displays the differences in interactions between the non-response and response groups to anti-PD-1 treatment. B Spatial localization of LGMN+ macrophages using Cell2location on the samples, with color intensity representing the infiltration abundance. C Chord diagram displaying the network of CXCL signaling pathways between subpopulations in the spatial transcriptomic atlas. D Scatter plot showing the expression correlation between LGMN and CXCL16 in the TCGA-STAD cohort. E Scatter plot illustrating the expression correlation between RUNX3 and CXCR6 in the TCGA-STAD cohort

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