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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Metastasis and basement membrane-related signature enhances hepatocellular carcinoma prognosis and diagnosis by integrating single-cell RNA sequencing analysis and immune microenvironment assessment

Fig. 7

Immunological analysis of LIHC patients in respective risk groups. (A, B) ssGSEA scores for immune cells and immune function in TCGA cohort. (C) Correlation between ITGA3 expression and enrichment of immune cells. (D) Correlation between ITGA3 expression and macrophage enrichment. (E) Correlation between ITGA3 expression and Treg enrichment. ns = p > 0.05 (not significant), *p < 0.05, **p < 0.01, ***p < 0.001. Abbreviations: APC, antigen-presenting cell; aDC, activated dendritic cell; CCR, chemokine receptor; DC, dendritic cell; HLA, human leukocyte antigen; iDC, immature dendritic cell; INF, interferon; ITGA3, integrin subunit alpha 3; LIHC, liver hepatocellular carcinoma; MHC, major histocompatibility complex; NK, natural killer; pDC, plasmacytoid dendritic cell; ssGSEA, single-sample gene set enrichment analysis; TCGA, The Cancer Genome Atlas; Tfh, T follicular helper; TIL, tumor-infiltrating; Treg, regulatory T cell

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Journal of Translational Medicine

ISSN: 1479-5876

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