Fig. 3

Construction and validation of the MBRGs prognostic model. (A) Kaplan-Meier curve displaying OS of TCGA dataset. (B) ROC curve for TCGA dataset. (C) Risk curve and survival status for TCGA dataset. (D) PCA and t-SNE graph for TCGA dataset. (E) Kaplan-Meier curve displaying OS of the ICGC dataset. (F) ROC curve for the ICGC dataset. (G) Risk curve and survival status for the ICGC dataset. (H) PCA and t-SNE graph for the ICGC dataset. Abbreviations: AUC, area under the curve; ICGC, International Cancer Genome Consortium; MBRGs, metastasis and basement membrane-related genes; OS, overall survival; PCA, principal component analysis; ROC, receiver operating characteristic; TCGA, The Cancer Genome Atlas; t-SNE, t-distributed stochastic neighbor embedding