Fig. 10

Results of multi-omics correlation analysis A Correlation graph of key microbiota-key genes-key metabolites. The triangle graph represents the correlation graph of 11 key metabolites. The connecting line presented in orange representing negative correlation; a green line representing positive correlation. The thickness of the line represents Spearman’s correlation coefficient “r”. B Heatmap of the correlation between CBLB and 39 DEGs (from B vs. A). C Heatmap of the correlation between CBLB and 6 differential metabolites (from B vs. A). D The correlation analysis of CBLB and g_Robinsoniella|s_Robinsoniella_sp (from B vs. A). E Heatmap of the correlation between CBLB and 13 DEGs (from C vs. B). F Heatmap of the correlation between CBLB and 5 differential metabolites (from C vs. B). G The correlation analysis of CBLB and Violaceinic_acid (from C vs. B). The correlation heatmaps exclusively visualize pairs of relationships that meet the criteria of |r > 0.3| and P < 0.05