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Table 1 The performance of TAGMe assessment stratified by different clinical characteristics

From: Hypermethylated TAGMe as a universal-cancer-only methylation marker and its application in diagnosis and recurrence monitoring of urothelial carcinoma

Clinical characteristics

TAGMe positive

Urothelial Carcinoma

Sensitivity (95% CI)

Invasiveness

 NMIUC

211

247

85.4% (80.4–89.6%)

 MIUC

120

130

92.3% (86.3–96.3%)

Grade

 Low grade

75

97

77.3% (67.7–85.2%)

 High grade

231

253

91.3% (87.1–94.5%)

Tumor numbers

 Single

149

171

87.1% (81.2–91.8%)

 Multiple

129

148

87.2% (80.7–92.1%)

Tumor size

 < 1 cm

32

38

84.2% (68.8–94.0%)

 1–3 cm

145

169

85.8% (79.6–90.7%)

 > 3 cm

92

102

90.2% (82.7–95.2%)