Fig. 4
From: Systematic review of fatigue severity in ME/CFS patients: insights from randomized controlled trials

Fatigue severity by case definition of ME/CFS, continent, fatigue assessment tool and publication year. Fatigue severity (out of 100) was calculated and analyzed by case definition of ME/CFS (A), continent where the patients lived (B), fatigue assessment tool (C), and publication year (D). Each dot represents the value of each study included in this article. The mean score was represented by a horizontal line inside the square, while the 95% CI was depicted by the range of square. *Meta-analysis was done together for each subgroup