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Table 2 Blood serum low abundant proteins differentially enriched in strong recoverers (SR) or non-recoverers (NR)

From: Untargeted blood serum proteomics identifies novel proteins related to neurological recovery after human spinal cord injury

Gene name

Protein name

log2FC

(NR vs. SR)

SR enrichement

(folds)

NR enrichment

(folds)

p-value

FDR

ELISA

CALU

Calumenin

-1.047

2.07

 

2.6E-05

0.037

✓*

SERPINE1

Serpin family E member 1

-1.144

2.21

 

2.8E-05

0.037

✓

CTSW

Cathepsin W

-0.735

1.66

 

1.6E-04

0.068

 

RAP1B/RAP1A

Ras-related protein Rap-1B

-0.700

1.62

 

2.3E-04

0.068

 

ANGPT1

Angiopoietin-1

-0.748

1.68

 

2.4E-04

0.068

✓

ARHGAP35

Rho GTPase activating protein 35

-1.587

3

 

6.8E-04

0.091

✓

FKBP4

FKBP prolyl isomerase 4

-0.945

1.92

 

7.4E-04

0.091

 

FHOD1

FH1/FH2 domain-containing protein 1

-0.794

1.73

 

7.5E-04

0.091

 

B4GALT7

Beta-1.4-galactosyltransferase 7

-0.979

1.97

 

8.7E-04

0.094

 

CNDP1

Beta-Ala-His dipeptidase

-0.713

1.64

 

9.9E-04

0.094

 

PIN1

PDZ domain containing 2

-1.158

2.23

 

1.2E-03

0.094

✓

TCN2

Transcobalamin-2

-0.700

1.62

 

1.6E-03

0.096

✓

AGER

Advanced glycosylation end product-specific receptor

0.968

 

1.96

5.4E-05

0.048

✓

DEFA1/DEFA3

Defensin alpha 1 / Defensin alpha 3

1.147

 

2.21

4.1E-04

0.078

✓

ITPA

Inosine triphosphate pyrophosphatase

0.826

 

1.77

6.5E-04

0.091

 

BPIFB2

BPI fold containing family B member 2

1.419

 

2.67

1.0E-03

0.094

 

UPB1

Beta-ureidopropionase

0.806

 

1.75

1.2E-03

0.094

 

ADM

Pro-adrenomedullin

0.689

 

1.61

1.3E-03

0.094

 

RACK1

Small ribosomal subunit protein RACK1[…]

1.067

 

2.09

1.4E-03

0.095

✓*

STXBP5

Syntaxin binding protein 5

0.897

 

1.86

1.4E-03

0.095

 

LSM1

LSM1 homolog. mRNA degradation associated

0.922

 

1.89

1.5E-03

0.095

 

OLR1

Oxidized low-density lipoprotein receptor 1

1.125

 

2.18

1.7E-03

0.096

✓*

CTSG

Cathepsin G

0.973

 

1.96

1.7E-03

0.096

✓

CD300A

CMRF35-like molecule 8

0.900

 

1.86

1.7E-03

0.096

✓

  1. ✓ Selected for ELISA validation; * Current available kits not sensitive enough for a reliable evaluation of the protein in our samples