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Table 2 Bladder Fibrosis Imaging – Pros/Cons with respects to the gold standard

From: Radiology of fibrosis part III: genitourinary system

Lung Fibrosis Imaging

Cytoscopy1

PROs

Direct, Allows for biopsy, Real time, No ionizing radiation

CONs

Operator dependent, Invasive, Small field of view, Only gross morphological discrimination

Multiphasic CT Urography

PROs

Findings found to be linked to clinical manifestations and histopathology of IC/BPS, High sensitivity/specificity, Low acquisition time, Readily available

CONs

Use of ionizing radiation

MRI2

PROs

High contrast, High spatial resolution, Non-invasive, No ionizing radiation, Readily available

CONs

Use of contrast agents, High cost

US

PROs

Low-cost, Readily available, Well tolerated, No ionizing radiation

CONs

Low sensitivity unless paired with CT, Operator dependent, Dependent on patient habitus

  1. 1Gold standard, 2Promising future techniques