Fig. 1

Analysis of specific cell-dependent genes in colorectal cancer and identification of a 22-gene prognostic signature. (A) Flow diagram of identifying the 22-gene colorectal cancer (CRC) fitness gene signature (CFG22 score). (B) Heat map shows gene effects of 22 genes identified in the prognostic signature. (C). The correlation between 22 genes and univariate test of each gene in the GSE39582 cohort. (D) Kaplan-Meier assessment of overall survival according to the CFG22 score in GSE39582 cohort. (E) One, three, five-year receiver operator characteristic (ROC) curves of overall survival for GSE39582 cohort. OS, overall survival