Fig. 1
NSUN2 and RNA m5C methylation level is highly expressed in DR. (A) The target gene NSUN2 was significantly differentially expressed according to the Microarray analysis. (B) NSUN2 mRNA expression in DR and non-DR patient samples. (C) NSUN2 mRNA expression in DB/M versus DB/DB mice. (D) NSUN2 protein expression in DB/M versus DB/DB mice. (E) Differential immunofluorescence staining for NSUN2 in DB/M and DB/DB mice. (F) Differential expression of NSUN2 mRNA at the cellular level. (G) Differential expression of the NSUN2 protein at the cellular level. (H) Differences in RNA m5C levels in DB/M and DB/DB mice. I Differences in RNA m5C at the cellular level