Table 2 Results of ROC curve analysis and logistic regression in the discovery cohort

Cer(d18:0/24:0)

0.76

< 0.001

0.20 (0.09–0.47)

< 0.001

0.08 (0.02–0.25)

Cer(d18:0/22:0)

0.74

< 0.001

0.23 (0.10–0.52)

< 0.001

0.10 (0.03–0.30)

Cer(d42:3)

0.72

0.001

0.21 (0.08–0.54)

< 0.001

0.09 (0.02–0.32)

SM(d22:0/16:0)

0.76

< 0.001

0.19 (0.08–0.46)

< 0.001

0.06 (0.01–0.25)

SM(d18:1/24:1)

0.82

< 0.001

0.04 (0.01–0.21)

< 0.001

0.01 (0.00-0.09)

SM(d42:0)

0.73

< 0.001

0.18 (0.07–0.51)

< 0.001

0.05 (0.01–0.20)

SM(d40:0)

0.76

< 0.001

0.15 (0.06–0.39)

< 0.001

0.03 (0.01–0.16)

SM(d39:0)

0.77

< 0.001

0.26 (0.13–0.53)

< 0.001

0.19 (0.08–0.45)

SM(d38:0)

0.78

< 0.001

0.18 (0.08–0.42)

< 0.001

0.05 (0.01–0.19)

SM(d36:0)

0.72

0.001

0.28 (0.13–0.60)

< 0.001

0.19 (0.08–0.48)

SM(d20:1/16:1)

0.94

< 0.001

44.85 (8.86-226.99)

< 0.001

59.91 (9.18-391.17)

SM(d34:1)

0.85

< 0.001

8.39 (3.05–23.14)

< 0.001

7.81 (2.83–21.61)

LPC(18:2)

0.88

< 0.001

59.23 (8.85-396.59)

< 0.001

108.93 (11.07-1072.03)

LPC(16:0)

0.83

< 0.001

26.44 (5.26-132.79)

< 0.001

45.67 (6.79-307.57)

PC(34:2)

0.89

< 0.001

2.76 (1.84–4.15)

< 0.001

3.55 (2.00-6.29)