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Table 1 Characteristics and baseline of patients

From: Deep learning based digital pathology for predicting treatment response to first-line PD-1 blockade in advanced gastric cancer

 

FAH-SYSU

FAH-NAU

SAH-SYSU

ACH-GZMU

Total

Characteristics

Patients (139)

Patients(90)

Patients (25)

Patients (10)

264

Age

     

Mean (SD)

56.7 (12.9)

58.0 (11.7)

59.1 (11.7)

57.0 (12.0)

57.3 (12.9)

Median [Min, Max]

58.0 [26.0, 88.0]

58.5 [22.0, 86.0]

59.0 [22.0, 86.0]

59.5 [30.0, 70.0]

58.5 [22.0, 88.0]

Sex

     

Female

35 (25.2%)

35 (38.9%)

24 (39.3%)

1 (10.0%)

77 (29.2%)

Male

104 (74.8%)

55 (61.1%)

37 (60.7%)

9 (90.0%)

187 (70.8%)

Disease region

     

Localized

46 (33.1%)

3 (3.3%)

2 (3.3%)

1 (10.0%)

56 (21.2%)

Metastatic

93 (66.9%)

87 (96.7%)

59 (96.7%)

9 (90.0%)

208 (78.8%)

Differentiation

     

Moderate

27 (19.4%)

32 (35.6%)

23 (37.7%)

1 (10.0%)

64 (24.6%)

Poor

112 (80.6%)

58 (64.4%)

38 (62.3%)

9 (90.0%)

199 (75.4%)

Primary Site

     

Lower

45 (32.4%)

34 (37.8%)

23 (37.7%)

4 (40.0%)

92 (34.8%)

Middle

52 (37.4%)

42 (46.7%)

34 (55.7%)

3 (30.0%)

107 (40.5%)

Upper

42 (30.2%)

14 (15.6%)

4 (6.6%)

3 (30.0%)

65 (24.6%)

Reaction

     

Well reaction

    

128 (48.4%)

iCR

1 (0.8%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1 (0.4%)

iPR

67 (48.2%)

43 (47.8%)

13 (52%)

4 (40.0%)

127 (48.1%)

Poor reaction

    

136 (51.6%)

iSD

38 (27.3%)

29 (32.2%)

4 (16%)

5 (50.0%)

76 (28.8%)

iPD

33 (23.7%)

18 (20.0%)

8 (32%)

1 (10.0%)

60 (22.7%)

WSIs

159 (50.8%)

100 (31.9%)

44 (14.1%)

10 (3.2%)

313

  1. iCR: immune complete response; PR: immune partial response; iSD: immune stable disease; iPD: immune progressive disease; WSI: whole slide image