Table 4 Sensitivity, specificity, and predictive values calculated for both the discovery and validation cohorts according to two pre-stablished cutoffs based on the discovery cohort. The aim was to distinguish between AIN and ATN. Cutoff A corresponds to the 75th percentile of uMCP in patients with ATN from the discovery cohort, whereas cutoff B corresponds to the 50th percentile of uMCP in the same group. AIN-Acute interstitial nephritis; ATN – acute tubular necrosis

From: Immune checkpoint inhibitors induce acute interstitial nephritis in mice with increased urinary MCP1 and PD-1 glomerular expression