Fig. 2

Performance assessment of SV callers. A The generation of SV simulation data. B The average detection rate of SV callers. C Circos plots exhibit the detection rates of each custom SV in SV simulation data for Delly (blue), SvABA (orange), Lumpy (green), and Manta (red). Each connection in the center of the circos plot represents the fusion of genes at both ends. The concentric rings proceed from outermost to innermost, signifying VAF values of 0.5, 1.0, 2.0, 5.0, and 10.0, respectively. The height of the barplot on each ring denotes the detection count of the corresponding SV