Fig. 1

Effect of BI-9740 on bone marrow neutrophil serine protease activation. A Activities of neutrophil elastase (NE) and cathepsin G (CatG) and B Western blotting analysis of NE in bone marrows from placebo and BI-9740-treated rats. The upper blot was incubated with anti-NE, and the lower blot was incubated with anti-myeloperoxidase (MPO) for use as the loading control. Values are presented as mean ± SEM. *p < 0.05 vs. placebo