Table 2 Odds ratios of DNA virus infection in ME/CFS patients
From: Evaluation of viral infection as an etiology of ME/CFS: a systematic review and meta-analysis
Infection | PCR | Antibody detection | ||
|---|---|---|---|---|
(Number. of study, PCR/Ab) | Number. of patients/controls | Odds ratio | Number. of patients/controls | Odds ratio |
| Â | [95% CI] | [95% CI] | ||
Enveloped DNA virus | ||||
 HHV-1, 2, 3 (0/1) | None | Healthy (65/87) | 0.93 [0.60, 1.45] | |
 EBV (HHV-4) (6/8) | Healthy (374/256) | 0.84 [0.54, 1.31] | Healthy (666/396) | 1.26 [0.83, 1.91] |
| Â | Â | MS (250/49) | 1.81 [0.82, 3.99] | |
| Â | Â | FM (65/11) | 1.20[0.13, 11.37] | |
| Â | Â | Non-ME/CFS (10/28) | Not estimable* | |
| Â | Â | CF(101/35) | 1.06 [0.31, 3.56] | |
 CMV (HHV-5) (2/5) | Healthy (80/72) | 0.91 [0.40, 2.08] | Healthy (395/255) | 0.70 [0.49, 1.01] |
| Â | Â | MS (250/40) | 0.52 [0.27, 1.03] | |
| Â | Â | FM (65/11) | 0.29 [0.06, 1.47] | |
| Â | Â | Non-ME/CFS (165/34) | Not estimable | |
 HHV-6 (13/11) | Healthy (768/510) | 1.47 [1.10, 1.98] | Healthy (853/587) | 1.42 [1.00, 2.01] |
CF (3/2) | 3.00 [0.08, 115.34] | MS (250/40) | 1.21 [0.39, 3.73] | |
Non-ME/CFS (8/7) | 0.83 [0.08, 8.24] | FM (65/11) | 1.09 [0.21, 5.76] | |
 HHV-7 (6/4) | Healthy (255/213) | 1.67 [1.07, 2.60] | Healthy (228/217) | 2.28 [1.39, 3.73] |
| Â | Â | FM (65/11) | 1.67 [0.40, 6.88] | |
 HHV-8 (2/2) | Healthy (22/22) | Not estimable | Healthy (57/47) | 0.58 [0.11, 3.14] |
Non-ME/CFS (8/7) | Not estimable | Â | Â | |
 HSV-1 (1/2) | Healthy (30/16) | 1.07 [0.09, 12.81] | Healthy (272/128) | 1.18 [0.77, 1.81] |
| Â | Â | MS (250/40) | 0.59 [0.30, 1.16] | |
 HSV-2 (0/2) | None | Healthy (272/128) | 1.27 [0.80, 2.00] | |
MS (250/40) | 0.97 [0.49, 1.91] | |||
 VZV (1/2) | Healthy (22/22) | Not estimable | Healthy (250/106) | 0.58 [0.12, 2.79] |
| Â | Â | MS (250/40) | 0.78 [0.09, 6.37] | |
Non-enveloped DNA virus | ||||
 Parvovirus B19 (4/3) | Healthy (328/306) | 5.55 [2.61, 11.79] | Healthy (366/309) | 4.33 [1.22, 15.37] |
 JC virus (1/0) | Healthy (22/22) | Not estimable | None | |
 BK virus (1/0) | Healthy (22/22) | Not estimable | None | |