Skip to main content
Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Downregulation of SMIM3 inhibits growth of leukemia via PI3K-AKT signaling pathway and correlates with prognosis of adult acute myeloid leukemia with normal karyotype

Fig. 6

SMIM3 knockdown reduced the proliferation of AML cells in nude mice by inhibiting PI3K-AKT signaling pathway. A–D, F–I SMIM3-KD inhibits tumor growth in Kasumi-1 and THP-1 cells. E, J The expression of PI3K-AKT signaling pathway proteins in tumor tissues by Western blot. CTRL, control; KD, knockdown; ***P < 0.001 compared with CTRL cells

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us